Medicinal Chemistry

Contents: Preface. 1. Basic principles of medicinal chemistry. 2. Principles of drug design. 3. Drugs acting at autonomous nervous system. 4. Autocoids. 5. Drugs affecting uterine motility. 6. Steroids and related drugs. 7. Drugs acting on Central Nervous System. 8. Diuretics. 9. Cardiovascular drugs. 10. Anticoagulants and antiplatelet drugs. 11. Antimetabolites. 12. Chemotherapeutic agents. 13. Antineoplastic agents. 14. Antiviral drugs. 15. Immunosuppressives and immunostimulants. 16. Thyroid and antithyroid drugs. 17. Insulin and oral hypoglycaemic agents. 18. Drug metabolism. Bibliography. Index.

"This book has been designed to serve the needs of pharmacology students as an introductory manual on the field of medicinal or pharmaceutical chemistry. Written to meet the challenges of the ever changing curricula of medicinal chemistry course, it focuses on providing readers with a grasp over the fundamentals of medicinal chemistry, with a focus on the drug development process from the perspective of the pharmacist as a therapeutic clinical consultant, rather than as a mere chemist.

Beginning with the fundamental principles of chemistry, biology and biochemistry, which underlie the medicinal chemistry field, it undertakes a look at these principles to understand the properties, mode of action, therapeutic applications, and limitations of various pharmaceutical agents. In addition, it also analyses the challenges posed by new diseases, and the trends and advances in the field taking place currently.

The comprehensive and lucid content of the book, combined with its relevant and up-to-date information, serves well for all the readers." (jacket)