Principles of Medicinal Chemistry

Principles of Medicinal Chemistry explores the fundamental principles of medicinal chemistry, including drug-receptor interactions, structure-activity relationships (SAR), pharmacokinetics, and pharmacodynamics. It provides a thorough understanding of how molecular modifications influence drug behavior, efficacy, and safety. Key topics include rational drug design, combinatorial chemistry, prodrugs, and the role of computational chemistry in modern drug development. The book also highlights advanced techniques such as molecular docking, QSAR modeling, and bioisosterism, ensuring readers stay at the forefront of pharmaceutical innovation. Special emphasis is placed on the chemistry of major drug classes, from antibiotics and antivirals to anticancer and neuropharmacological agents. Principles of Medicinal Chemistry serves as an essential resource for students, researchers, and professionals in pharmaceutical sciences. It equips readers with the knowledge needed to understand drug action at a molecular level and contribute to the advancement of life-saving medicines.