Textbook of Pharmacology

Contents: Preface to Second Edition. Preface to First Edition. Section I: General Pharmacology: 1. Historical aspects and introduction, dosage forms and drug delivery systems. 2.  Pharmacokinetics—drug absorption, distribution, metabolism and elimination. 3.  Pharmacodynamics-mechanism of drug action, factors modifying drug effects, therapeutic drug monitoring, dose–response relationship. 4.  Adverse drug reactions, drug interactions and drug assay. 5.  Drug usage, essential drug concept and drug development. Section II: Drugs Acting on Autonomic Nervous System: 6. General considerations of autonomic nervous system and neurohumoral transmission. 7.  Adrenergic system and adrenergic drugs. 8.  Adrenergic blocking drugs. 9.  Cholinergic system and cholinergic drugs.10.  Anticholinergic drugs and drugs acting on autonomic ganglia. Section III: Drugs Acting on Cardiovascular System: 11. General considerations and antihypertensive drugs. 12.  Ischemic heart disease (IHD) and treatment of angina pectoris.13. Drugs for congestive heart failure.14. Drugs used in cardiac arrhythmias. Section IV: Drugs Acting on Kidney: 15. Diuretics. Section V: Drugs Acting on Central Nervous System: 16.  Organization and functioning of central nervous system and central neurotransmitters, sedatives and hypnotics. 17.  General anesthetics, skeletal muscle relaxants and local anesthetics. 18.  Therapeutic approaches to neurodegenerative and movement disorders. 19. Drug treatment of psychotic disorders. 20. Drug treatment of epileptic disorders. 21. Opioid analgesics. 22.  Nonsteroidal anti-inflammatory drugs (NSAIDs) and drugs for rheumatoid arthritis and gouty arthritis. 23. The alcohols and drugs of abuse. Section VI: Autacoids: 24.  Histamine, H1 Antagonists, 5-Hydroxytryptamine (5-HT), and 5-HT Agonists and Antagonists. 25.  Ergot Alkaloids, Eicosanoids, and Vasoactive Peptides. Section VII: Chemotherapeutic Agents: 26.  General considerations of antibiotics, sulfonamides, trimethoprim, quinolones and urinary antiseptics and analgesics. 27.  Penicillins, cephalosporins, the beta-lactam antibiotics and miscellaneous antibiotics. 28. Aminoglycosides. 29.  Tetracyclines and chloramphenicol. 30.  Macrolides, ketolides, clindamycin, streptogramins, oxazolidinediones and other antibiotic agents. 31.  Chemotherapy of tuberculosis and leprosy. 32.  Chemotherapy of protozoal infections. 33. Antiviral Agents and Anti-HIV drugs. 34.  Antifungal agents. 35. Anthelminthic agents. 36. Cancer chemotherapy. Section VIII: Endocrine Disorders and Therapeutic Considerations: 37.  Hypothalamic–pituitary hormones. 38.  Adrenocorticotropic hormones and adrenocortical steroids. 39. Thyroid hormones and antithyroid drugs. 40. Ovarian hormones. 41.  Androgens and antiandrogens. 42. Pancreatic hormones and antidiabetic drugs. 43. Drugs affecting bone mineral metabolism. Section IX: The Hemopoietic System: 44.  Drugs for iron-deficiency anemia. 45.  Drugs for megaloblastic anemia, hemopoietic growth factors. 46. Blood coagulation disorders. Section X: The Respiratory System: 47. Drugs for respiratory disorders. Section XI: Drugs for Gastrointestinal Disorders: 48. Drug treatment of acid peptic disorders. 49. Antiemetic drugs. 50. Drugs for motility disorders, purgatives and laxatives, antidiarrheal agents and drug treatment of irritable bowel syndrome and inflammatory bowel disease. Section 12: Miscellaneous Topics: 51. Drug therapy of hyperlipidemia. 52. Intravenous fluid therapy. 53. Immune pharmacology. 54. Therapeutic considerations of toxic disorders. 55. Dermatological pharmacology. 56. Drugs acting on the uterus. 57. Drug use during pregnancy. 58. The vitamins. Appendices.

Pharmacology is one of the fast-growing branches of medical science. This book deals with both basic information in the subject of Pharmacology as well as advanced aspects and pharmacological approaches for drug treatment of clinical conditions. Latest advancements in pharmacology during the recent past development of newer drugs for diabetes mellitus (newer insulins, GLP-1 analogs, DPP-4 inhibitors, SGLT-2 inhibitors), anti-TB drugs (bedaquilin), additional generations of cephalosporins, newer antimalignancy drugs  (monoclonal antibodies), and newer anti-HIV drugs (NNRTIs and protease inhibitors) have been incorporated in respective chapters. The book provides comprehensive information about drugs, including the pharmacokinetics, pharmacodynamics, clinical and diagnostic aspects of disease conditions, therapeutic indications, adverse reactions, and drug interactions. This second edition will serve as a basic textbook for undergraduate medical students and those preparing for postgraduate entrance examinations.